ES3

ES3, from Vitobest®, is a specially formulated formula to help us relax the mind and body, maintain our cognitive health, and improve post-exercise recovery time.

In obtaining ES3, Vitobest® incorporates ingredients that help to reduce stress levels:

• Phosphatidylserine: phospholipid capable of enhancing memory and decreasing its deterioration due to aging¹ and stress². Furthermore, it can accelerate post-exercise recovery, prevent muscle pain, and decrease cortisol concentration³ (a hormone related to increased stress levels).
• Theanine: an amino acid capable of crossing the blood-brain barrier and acting directly on the dopamine, serotonin, and gamma-aminobutyric acid (GABA) production centers; enabling an increase in the state of pleasure⁴ and a decrease in stress and anxiety levels⁵.
• Licorice extract (Glycyrrhiza glabra): contains glycyrrhizic acid, which acts directly on the adrenal gland inhibiting cortisol metabolism.
• Extract of Rhodiola rosea: exerts an anti-fatigue effect that can increase mental performance and decrease cortisol response to stress⁶.

Vitobest® uses vegetable capsules (VegeCaps) suitable for vegan diets for this supplement.

Bibliography:

¹"Effects of phosphatidylserine in age‐associated memory impairment". T. H. Crook, PhD et al. (May 1991). Neurology 41 (5): 644-649.

²"Milk-based phospholipids increase morning cortisol availability and improve memory in chronically stressed men". Melanie Schubert et al. (June 2011). Nutrition Research 31 (6): 413–420.

³"Phospholipids and sports performance". Jäger R, Purpura M, Kingsley M (7 of 2007). Journal of the International Society of Sports Nutrition 4: 5.

⁴"Antidepressant-like effects of L-theanine in the forced swim and tail suspension tests in mice". Yin C1, Gou L, Liu Y, Yin X, Zhang L, Jia G, Zhuang X. Phytother Res. 2011 Nov;25(11):1636-9. doi: 10.1002/ptr.3456. Epub 2011 Mar 21.

⁵"Neurobiological effects of the green tea constituent theanine and its potential role in the treatment of psychiatric and neurodegenerative disorders". Lardner Al. Nutr. Neurosci. 2014 Jul;17(4):145-55. doi: 10.1179/1476830513Y.0000000079. Epub 2013 Nov 26.

⁶"A randomized, double-blind, placebo-controlled, parallel-group study of the standardized extract SHR-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue". Erik M.G. Olsson, Bo von Schéele, Alexander G. Panossian. DOI 10.1055/s-0028-1088346 Planta Med. 2009; 75: 105-112.